{"id":575,"date":"2025-01-31T13:23:06","date_gmt":"2025-01-31T13:23:06","guid":{"rendered":"https:\/\/gujaratgastrohospital.in\/?page_id=575"},"modified":"2025-01-31T13:26:58","modified_gmt":"2025-01-31T13:26:58","slug":"ulcerative-colitis","status":"publish","type":"page","link":"https:\/\/gujaratgastrohospital.in\/ulcerative-colitis\/","title":{"rendered":"Ulcerative colitis"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"575\" class=\"elementor elementor-575\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9e55a47 e-con-full e-flex e-con e-parent\" data-id=\"9e55a47\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-4c55b56 elementor-widget elementor-widget-heading\" data-id=\"4c55b56\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.23.0 - 05-08-2024 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2 class=\"elementor-heading-title elementor-size-default\">Ulcerative colitis<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7d9a7fe e-con-full e-flex e-con e-parent\" data-id=\"7d9a7fe\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-069b1b1 e-con-full e-flex e-con e-child\" data-id=\"069b1b1\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-be6bbb3 elementor-widget elementor-widget-video\" data-id=\"be6bbb3\" data-element_type=\"widget\" data-settings=\"{&quot;youtube_url&quot;:&quot;https:\\\/\\\/youtu.be\\\/_2r0bIii2sw?si=kNs-t0EkneqJhwEM&quot;,&quot;video_type&quot;:&quot;youtube&quot;,&quot;controls&quot;:&quot;yes&quot;}\" data-widget_type=\"video.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.23.0 - 05-08-2024 *\/\n.elementor-widget-video .elementor-widget-container{overflow:hidden;transform:translateZ(0)}.elementor-widget-video .elementor-wrapper{aspect-ratio:var(--video-aspect-ratio)}.elementor-widget-video .elementor-wrapper iframe,.elementor-widget-video .elementor-wrapper video{height:100%;width:100%;display:flex;border:none;background-color:#000}@supports not (aspect-ratio:1\/1){.elementor-widget-video .elementor-wrapper{position:relative;overflow:hidden;height:0;padding-bottom:calc(100% \/ var(--video-aspect-ratio))}.elementor-widget-video .elementor-wrapper iframe,.elementor-widget-video .elementor-wrapper video{position:absolute;top:0;right:0;bottom:0;left:0}}.elementor-widget-video .elementor-open-inline .elementor-custom-embed-image-overlay{position:absolute;top:0;right:0;bottom:0;left:0;background-size:cover;background-position:50%}.elementor-widget-video .elementor-custom-embed-image-overlay{cursor:pointer;text-align:center}.elementor-widget-video .elementor-custom-embed-image-overlay:hover .elementor-custom-embed-play i{opacity:1}.elementor-widget-video .elementor-custom-embed-image-overlay img{display:block;width:100%;aspect-ratio:var(--video-aspect-ratio);-o-object-fit:cover;object-fit:cover;-o-object-position:center center;object-position:center center}@supports not (aspect-ratio:1\/1){.elementor-widget-video .elementor-custom-embed-image-overlay{position:relative;overflow:hidden;height:0;padding-bottom:calc(100% \/ var(--video-aspect-ratio))}.elementor-widget-video .elementor-custom-embed-image-overlay img{position:absolute;top:0;right:0;bottom:0;left:0}}.elementor-widget-video .e-hosted-video .elementor-video{-o-object-fit:cover;object-fit:cover}.e-con-inner>.elementor-widget-video,.e-con>.elementor-widget-video{width:var(--container-widget-width);--flex-grow:var(--container-widget-flex-grow)}<\/style>\t\t<div class=\"elementor-wrapper elementor-open-inline\">\n\t\t\t<div class=\"elementor-video\"><\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5a5fc44 e-con-full e-flex e-con e-child\" data-id=\"5a5fc44\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e0c3e17 elementor-widget elementor-widget-text-editor\" data-id=\"e0c3e17\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.23.0 - 05-08-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p><strong>Ulcerative Colitis (UC)<\/strong> is a <strong>chronic, relapsing-remitting inflammatory bowel disease (IBD)<\/strong> that primarily affects the <strong>colon (large intestine)<\/strong> and <strong>rectum<\/strong>.<\/p><p>It leads to continuous mucosal inflammation, resulting in ulcers and bleeding.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1cc6ae9 elementor-widget elementor-widget-text-editor\" data-id=\"1cc6ae9\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4><span style=\"text-decoration: underline;\"><strong>Pathophysiology<\/strong><\/span><\/h4>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a66c9e4 elementor-widget elementor-widget-text-editor\" data-id=\"a66c9e4\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul><li><strong>Triggering Event<\/strong> \u2192 A combination of genetic, immune, and environmental factors triggers an abnormal immune response.<\/li><li><strong>Immune Activation<\/strong> \u2192 Overactive <strong>T-cells<\/strong> (mainly <strong>Th2 cells<\/strong>) cause persistent inflammation.<\/li><li><strong>Mucosal Damage<\/strong> \u2192 Chronic inflammation leads to:<ul><li>Continuous ulceration of the colonic mucosa.<\/li><li>Loss of the protective mucus layer.<\/li><li>Increased permeability, leading to diarrhea and bleeding.<\/li><\/ul><\/li><li><strong>Disease Progression<\/strong> \u2192 Leads to complications like strictures, toxic megacolon, and colorectal cancer.<\/li><li>\u00a0<\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c2507f2 elementor-widget elementor-widget-text-editor\" data-id=\"c2507f2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4><span style=\"text-decoration: underline;\"><strong>Clinical Features<\/strong><\/span><\/h4>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-041934b elementor-widget elementor-widget-text-editor\" data-id=\"041934b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h3><strong>A. Symptoms<\/strong><\/h3><ol><li><p><strong>Gastrointestinal Symptoms<\/strong><\/p><ul><li><strong>Chronic bloody diarrhea<\/strong> (hallmark symptom)<\/li><li><strong>Mucus in stool<\/strong><\/li><li><strong>Urgency and tenesmus<\/strong> (feeling of incomplete evacuation)<\/li><li><strong>Abdominal pain<\/strong> (mostly lower left quadrant)<\/li><li><strong>Weight loss<\/strong> (severe cases)<\/li><\/ul><\/li><li><p><strong>Systemic Symptoms<\/strong> (in severe cases)<\/p><ul><li>Fatigue, fever, anemia<\/li><li>Malnutrition due to nutrient loss<\/li><\/ul><\/li><\/ol><h3><strong>B. Extraintestinal Manifestations (EIMs)<\/strong><\/h3><p>UC is not limited to the intestine; it can affect other organs:<\/p><ul><li><strong>Joints<\/strong>: Arthritis, ankylosing spondylitis<\/li><li><strong>Skin<\/strong>: Erythema nodosum, pyoderma gangrenosum<\/li><li><strong>Eyes<\/strong>: Uveitis, episcleritis<\/li><li><strong>Liver<\/strong>: Primary sclerosing cholangitis (PSC)<\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-aa9f2c1 elementor-widget elementor-widget-text-editor\" data-id=\"aa9f2c1\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h4><span style=\"text-decoration: underline;\"><strong>Classification &amp; Severity<\/strong><\/span><\/h4>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dc261e0 elementor-widget elementor-widget-text-editor\" data-id=\"dc261e0\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul><li><h3><strong> Based on Location<\/strong><\/h3><ol><li><strong>Proctitis<\/strong>: Only rectum involved (mildest form).<\/li><li><strong>Left-sided colitis<\/strong>: Involves rectum, sigmoid, and descending colon.<\/li><li><strong>Pancolitis<\/strong>: Involves the entire colon (severe disease).<\/li><\/ol><\/li><li><h3><strong>Based on Severity (Truelove and Witts Criteria)<\/strong><\/h3><table><thead><tr><th>Feature<\/th><th>Mild<\/th><th>Moderate<\/th><th>Severe<\/th><\/tr><\/thead><tbody><tr><td><strong>Stool Frequency<\/strong><\/td><td>&lt; 4\/day<\/td><td>4-6\/day<\/td><td>&gt; 6\/day with blood<\/td><\/tr><tr><td><strong>Blood in Stool<\/strong><\/td><td>Small amount<\/td><td>Moderate<\/td><td>Large amount<\/td><\/tr><tr><td><strong>Fever<\/strong><\/td><td>None<\/td><td>Possible<\/td><td>Yes (&gt;37.5\u00b0C)<\/td><\/tr><tr><td><strong>Heart Rate<\/strong><\/td><td>Normal (&lt;90 bpm)<\/td><td>Mildly elevated<\/td><td>&gt;90 bpm<\/td><\/tr><tr><td><strong>Hemoglobin<\/strong><\/td><td>Normal<\/td><td>Low<\/td><td>Severely low<\/td><\/tr><\/tbody><\/table><\/li><\/ul>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Ulcerative colitis https:\/\/youtu.be\/_2r0bIii2sw?si=kNs-t0EkneqJhwEM Ulcerative Colitis (UC) is a chronic, relapsing-remitting inflammatory bowel disease (IBD) that primarily affects the colon (large intestine) and rectum. It leads to continuous mucosal inflammation, resulting in ulcers and bleeding. Pathophysiology Triggering Event \u2192 A combination of genetic, immune, and environmental factors triggers an abnormal immune response. Immune Activation \u2192 Overactive [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-575","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Ulcerative colitis - Gujarat Gastro &amp; Vascular Hospital<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/gujaratgastrohospital.in\/ulcerative-colitis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ulcerative colitis - Gujarat Gastro &amp; Vascular Hospital\" \/>\n<meta property=\"og:description\" content=\"Ulcerative colitis https:\/\/youtu.be\/_2r0bIii2sw?si=kNs-t0EkneqJhwEM Ulcerative Colitis (UC) is a chronic, relapsing-remitting inflammatory bowel disease (IBD) that primarily affects the colon (large intestine) and rectum. 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